Diverticula are small, bulging pouches that can form in the lining of your digestive system. They are found most often in the lower part of the large intestine (colon). Diverticula are common, especially after age 40, and seldom cause problems. Sometimes, however, one or more of the pouches become inflamed or infected. That condition is known as diverticulitis. Diverticulitis can cause severe abdominal pain, fever, nausea and a marked change in your bowel habits. Mild diverticulitis can be treated with rest, changes in your diet and antibiotics. Severe or recurring diverticulitis may require surgery.
<p> The <b>TNFSF15</b> gene is a part of the tumor necrosis factor (TNF) family of cytokines; it has a role in cell proliferation, immune response and inflammatory reaction. Carriers of the risk allele G of the TNFSF15 gene have an increased risk of having to undergo surgical treatment for diverticulitis. Variants in the TNFSF15 gene do not determine the time required for the clinical manifestation of diverticulitis. </p>Test Details